Brain injections are a cornerstone technique in neuroscience research, enabling targeted delivery of viral vectors, tracers, or pharmacological agents into specific brain regions.
These (STEREOTAXIC???) injections are used for gene expression studies, optogenetic manipulation, neuronal circuit tracing, or localized drug delivery. Precision in both targeting and depth control is essential to achieve reproducible and interpretable experimental outcomes.
Manual stereotaxic brain injections are often prone to variability and technical challenges:
Flat skull positioning of the animal’s head required.
Manual drilling can lead to tissue damage. it requires trained personnel.
Manual depth control depends heavily on operator skill and may lead to inconsistent injection depths.
Even small angular misalignments or inaccuracies in skull leveling can result in off-target placements.
Difficulties when working in oblique trajectories due to poor angle resolution, calculation difficulties.
Injections performed without real-time feedback or motion correction can cause tissue damage or imprecise spread of injected material.
Repeatability between animals or operators is limited, complicating longitudinal or comparative studies.
Robot Steretoxic - Automated and error free brain injections
The Neurostar Robot Stereotaxic System automates the entire injection process, ensuring precision, repeatability, and tissue protection. Together, these features enable high-throughput, reproducible, and precise delivery of viral vectors or compounds — reducing user-dependent variability and improving experimental reliability.
Atlas-guided targeting
Integrated digital brain atlases and coordinate correction ensure accurate targeting even when the skull is not perfectly level.
Tilt correction
Automatically correct head alignment errors, ensuring micrometer precision without the need for perfect flat-skull leveling.
Automated depth control
The motorized injector moves with micrometer precision, allowing slow, consistent injection profiles that minimize reflux and tissue damage
Reproducible trajectories
Software-defined coordinates and motion parameters can be saved and reused for identical procedures across animals.
Smart BregmaFinder
Integrated cameras ensure consistent Bregma detection, real-time monitoring, and documentation for user-independent results.
Atlas scaling
The software adapts the atlas to size and age, ensuring consistent targeting across species and stages.
Ulttra-precise Injection control
Continuous and precisely controlled injection rates, even in the picoliter range.
Injection during movement
The needle can move slowly during injection, ensuring an optimal spread and minimal backflow.
Precise drilling calculation
Automatic computation of burr holes, even in not perfectly leveled animals
Automatic Drilling with Breakthrough detection
Simple and precise drilling through automated breakthrough recognition prevents tissue damage
Automatic synchronization
Drill and injector (needle or capillary) are fully synchronized — no manual reconfiguration or tool exchange after drilling is required.
Oblique trajectories
Access deep or lateral brain structures with the Smart Angle Device, guaranteeing smooth, repeatable trajectories and perfect alignment with specific atlas coordinates.
Flexible configuration for different applications
Neurostar offers a powerful suite of automated stereotaxic tools that elevate your neuroscience research. Engineered for flexibility and ease of use, our system adapts to your workflow, seamlessly interchanging tools, integrating accessories, and expanding with add-ons to keep pace with your most ambitious experiments.
Drill and MicroInjection Robot
Experience a new level of precision and efficiency. The Drill & Microinjection Robot combines automated drilling and injection in one continuous workflow — no recalibration, no tool change. Simply load the syringe and proceed with successive injections in the same or different animals with consistent accuracy every time.
Optogenetics Robot
Combine drilling, viral injection, and ferrule positioning in one seamless, synchronized workflow. Compatible with both syringes and glass capillaries, the Optogenetics Robot delivers precise viral targeting and consistent ferrule placement — without recalibration or manual tool exchange.
Smart BregmaFinder
Detect bregma precisely and monitor skull alignment in real time. The Smart BregmaFinder guides you to the correct reference position and records every movement — ensuring reproducible targeting and transparent documentation throughout the procedure.
Drill & Nanoinjection Robot
Automated drilling meets nanoliter precision. Perform delicate, contamination-free injections through glass capillaries — no recalibration, no tool change, just flawless targeting every time.
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Get in touch for a personalized setup
Don’t see your exact setup listed? Chances are we already have the right configuration for you. Get in touch, and we’ll help you find the combination of tools and accessories that best matches your research needs.
